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1.
Biofizika ; 45(4): 716-22, 2000.
Article Ru | MEDLINE | ID: mdl-11040983

The functional state of the synthetic apparatus of animal blood lymphocytes under weak low-frequency magnetic fields was studied. The changes in blood cell synthetic activity and leukocyte formula, a signal index of general nonspecific adaptation reactions, were shown. In the majority of cases examined, the variable magnetic fields increase the functional activity of the lymphocyte synthetic apparatus, improve the type of adaptation reaction, and enhance the level of immune resistance of the organism.


Lymphocytes/radiation effects , Magnetics , Adaptation, Physiological , Animals , Lymphocytes/immunology , Lymphocytes/metabolism , Male , Rats
2.
Biofizika ; 41(4): 898-905, 1996.
Article Ru | MEDLINE | ID: mdl-8962890

It is shown that general nonspecific adaptational reactions are the basis for mechanism of magnetic field effects at the organism level. The character of changes in organism and its subsystems (pattern of a general nonspecific adaptational reactions) is determined by the type of the reaction developing under magnetic field: stress or unknown before antistress reactions of training, calm activation and enhanced activation. The protection and damages under stress are interwoven, homeostatic parameters go beyond norm. Patterns of antistress general nonspecific adaptational reactions are within norm: for training reaction-within the lower half, calm activation-upper half, enhanced activation-somewhat above norm. The induction and frequency dependence of the reactions is periodical: as the parameters are changed to a certain coefficient a regular reiteration of general nonspecific adaptational reactions as topologically invariant transformations is observed at different reactivity levels of organism. General nonspecific adaptational reactions of superior reactivity levels (under weak of magnetic fields of lowest frequency) are more favourable, general nonspecific adaptational reactions of low levels have features of strain, desynchronization. Antistress general nonspecific adaptational reactions, especially activation reaction of superior reactivity levels, enhance nonspecific resistance, in contrast to stress without any damages or waste of energy, produce antitumor, protective (in reference to toxic agents and X-radiation) and rejuvenation effects, promoting self-organization. Regularities of general nonspecific adaptational reactions correspond to complex unequilibrium systems behavior.


Adaptation, Physiological , Magnetics , Homeostasis
3.
Vopr Onkol ; 37(2): 184-90, 1991.
Article Ru | MEDLINE | ID: mdl-2014697

In 59 patients with cancer of the vulva, levels of ACTH, FSH, thyrotropin, prolactin, somatotropin, cortisol, triiodothyronine, thyroxin, testosterone, progesterone and estradiol were measured in blood whereas those of 17-HOCS, 17-CS and estrogens--in urine. Hormonal imbalance was established at all levels of the endocrine system, viz. increased concentrations of cortisol and 17-HOCS, decreased ACTH level, shift in androgen/estrogen and androgen/progestin ratios towards testosterone, lowered FSH and somatotropin output and elevated blood-prolactin level.


Vulvar Neoplasms/etiology , Female , Hormones/analysis , Humans , Neoplasm Staging , Vulvar Neoplasms/metabolism , Vulvar Neoplasms/pathology
4.
Vopr Onkol ; 36(10): 1210-4, 1990.
Article Ru | MEDLINE | ID: mdl-2251816

Levels of tropic hormones of the pituitary, glucocorticoids and male and female sex hormones were assayed in 17 cases of kraurosis and leukoplakia of the vulva prior to treatment. Most patients revealed an abnormally high androgen/estrogen ratio, elevated level of glucocorticoids and low concentrations of thyrotropic hormone, prolactin and T3. The above disturbances are closely related and interdependent.


Leukoplakia/etiology , Vulvar Lichen Sclerosus/etiology , Vulvar Neoplasms/etiology , Adult , Endocrine Glands/physiopathology , Female , Follicular Phase/physiology , Humans , Leukoplakia/blood , Leukoplakia/physiopathology , Luteal Phase/physiology , Vulvar Lichen Sclerosus/blood , Vulvar Lichen Sclerosus/physiopathology , Vulvar Neoplasms/blood , Vulvar Neoplasms/physiopathology
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